Description

4-Pyridinecarboxamide, n-(5-((2-Chlorophenyl)Methylene)-4-Oxo-2-Thioxo -3-Thiazolidinyl)- is a specialized heterocyclic organic compound featuring a unique molecular architecture combining pyridine, thiazolidinone, and chlorophenyl moieties. This complex structure makes it a valuable advanced pharmaceutical intermediate and a key scaffold for research into novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting metabolic and inflammatory pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Research: Acts as a potential enzyme inhibitor or modulator in biochemical assays due to its thioxo-thiazolidinyl structure.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.
• Agrochemical Research: Investigated as a precursor for developing new agrochemicals with potential herbicidal or pesticidal activity.

Basic Information

Product Name	4-Pyridinecarboxamide, n-(5-((2-Chlorophenyl)Methylene)-4-Oxo-2-Thioxo -3-Thiazolidinyl)-
CAS No.	68710-98-5
Molecular Formula	C16H10ClN3O2S2
Molecular Weight	375.86 g/mol
Synonyms	N-[5-[(2-Chlorophenyl)methylene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]pyridine-4-carboxamide; 4-Pyridinecarboxamide, N-[5-[(2-chlorophenyl)methylene]-4-oxo-2-thioxo-3-thiazolidinyl]-; 3-(4-Pyridinylcarbonyl)amino-5-(2-chlorobenzylidene)-2-thioxo-4-thiazolidinone; 5-(2-Chlorobenzylidene)-3-(isonicotinoylamino)-2-thioxo-4-thiazolidinone; (Z)-5-(2-Chlorobenzylidene)-3-(isonicotinamido)-2-thioxothiazolidin-4-one
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay purity, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.