Description

2-Fluoro-5-Nitrophenyl Isocyanate is a specialized aromatic isocyanate derivative, distinguished by its reactive isocyanate (-NCO) group and electron-withdrawing nitro and fluoro substituents. This molecular architecture makes it a highly valuable and versatile building block for synthesizing complex organic molecules, particularly in the development of advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in medicinal chemistry and polymer science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of urea and carbamate derivatives, which are core structures in various drug candidates, particularly for targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Polymer Modification: Serves as a coupling agent or cross-linker to introduce specific functional groups into polymer chains, modifying properties like adhesion, thermal stability, or biocompatibility.
• Liquid Crystal and OLED Material Research: Employed in the creation of advanced organic electronic materials due to its ability to form rigid, conjugated structures.
• Chemical Probe Development: Utilized in biochemical research to label or modify proteins and other biomolecules, aiding in diagnostic and mechanistic studies.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized azo dyes and pigments with unique coloristic properties.

Basic Information

Product Name	2-Fluoro-5-Nitrophenyl Isocyanate
CAS No.	68622-14-0
Molecular Formula	C7H3FN2O3
Molecular Weight	182.11 g/mol
Synonyms	1-Fluoro-2-isocyanato-4-nitrobenzene; 2-Fluoro-5-nitrobenzenisocyanate; 5-Nitro-2-fluorophenyl isocyanate; (2-Fluoro-5-nitrophenyl)carbimidoic acid; Isocyanic acid, 2-fluoro-5-nitrophenyl ester; 2-Fluoro-5-nitro phenyl isocyanate
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Nitrophenyl Isocyanate is produced and tested under stringent quality management protocols to ensure high purity, consistency, and traceability. Our quality control system is designed to meet the exacting standards of pharmaceutical and advanced material research. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent degradation by atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.