Description

Sodium Alpha,Alpha,4-Trimethylcyclohex-3-Ene-1-Methanolate is a specialized organometallic reagent used as a key intermediate in advanced organic synthesis. This compound matters for its role as a sterically hindered, moisture-sensitive base or nucleophile, enabling precise chemical transformations that are difficult to achieve with standard reagents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing sterically hindered tertiary alcohol or ether motifs.
• Asymmetric Synthesis: Serves as a chiral building block or a base in enantioselective reactions for producing optically active compounds.
• Agrochemical Synthesis: Employed in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific cyclohexene-based structures.
• Fine Chemical Production: Acts as a precursor for fragrances, flavors, and specialty polymers where the trimethylcyclohexene moiety is desired.
• Catalyst Ligand Precursor: Utilized in the development of novel organometallic catalysts for polymerization or cross-coupling reactions.
• Material Science Research: Investigated for creating novel organic frameworks or metal-organic complexes with specific properties.

Basic Information

Product Name	Sodium Alpha,Alpha,4-Trimethylcyclohex-3-Ene-1-Methanolate
CAS No.	68540-43-2
Molecular Formula	C10H17NaO
Molecular Weight	176.23 g/mol
Synonyms	Sodium 1-Hydroxy-2,2,4-trimethyl-3-cyclohexene-1-methanolate; Sodium Trimethylcyclohexenemethanolate; 3-Cyclohexene-1-methanol, 1-hydroxy-2,2,4-trimethyl-, sodium salt; Sodium (2,2,4-Trimethyl-3-cyclohexen-1-yl)methanolate; Sodium 4-TMCHM; Sodium salt of Alpha,Alpha,4-Trimethyl-3-cyclohexene-1-methanol
EINECS	Contact for details

Quality Control

Our Sodium Alpha,Alpha,4-Trimethylcyclohex-3-Ene-1-Methanolate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent degradation from moisture and air. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (by Titration)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.