Description

3-Hydroxy-13,17-Secoandrostan-17-Oic-13,17-Lactam (4-(Bis(2-Chloroethyl)Amino)Phenyl)Butyrate is a complex, high-purity synthetic steroid derivative with significant research and pharmaceutical development potential. This compound is valued for its precise molecular architecture, which serves as a critical intermediate or active moiety in advanced therapeutic research. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel steroid-based agents, particularly in oncology and endocrinology.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel steroid-derived therapeutic agents.
• Oncology Research: Investigated for its potential as a targeted prodrug or cytostatic agent due to the nitrogen mustard moiety.
• Biochemical Research: Used as a reference standard or probe in steroid hormone receptor studies and metabolic pathway analysis.
• Fine Chemical Synthesis: Serves as a specialized precursor for creating more complex steroid-lactam hybrid molecules.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry projects and structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-Hydroxy-13,17-Secoandrostan-17-Oic-13,17-Lactam (4-(Bis(2-Chloroethyl)Amino)Phenyl)Butyrate
CAS No.	68426-41-5
Molecular Formula	C31H43Cl2N2O4
Molecular Weight	578.59 g/mol
Synonyms	4-[Bis(2-chloroethyl)amino]phenyl 3-hydroxy-13,17-secoandrostane-17-oate-13,17-lactam; Estramustine Lactam Derivative; NSC 686526; 13,17-Secoandrostane-17-oic acid, 3-hydroxy-, 13,17-lactam, 4-[bis(2-chloroethyl)amino]phenyl ester; Phenyl 4-[bis(2-chloroethyl)amino]butyrate derivative of 3-hydroxy-13,17-secoandrostan-17-oic acid 13,17-lactam
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high purity. Quality is verified through analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.