Description

3-(3-Iodo-Phenyl)-3-Oxo-Propionic Acid Ethyl Ester is a high-purity, versatile aryl ketoester building block essential for advanced organic synthesis. This compound is valued for its reactive β-ketoester and aryl iodide functional groups, enabling its use in complex coupling reactions and heterocyclic chemistry. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of compounds with aryl or heteroaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for organic electronic materials, liquid crystals, and specialty polymers.
• Cross-Coupling Reactions: The aryl iodide moiety makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings.
• Heterocyclic Chemistry: The β-ketoester group is utilized in the construction of various heterocyclic scaffolds, including pyrazoles, isoxazoles, and pyrimidines.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry in both academic and industrial R&D settings.

Basic Information

Product Name	3-(3-Iodo-Phenyl)-3-Oxo-Propionic Acid Ethyl Ester
CAS No.	68332-33-2
Molecular Formula	C11H11IO3
Molecular Weight	318.11 g/mol
Synonyms	Ethyl 3-(3-Iodophenyl)-3-oxopropanoate; 3-Oxo-3-(3-iodophenyl)propanoic Acid Ethyl Ester; 3-(3-Iodobenzoyl)propionic Acid Ethyl Ester; β-Keto Ester of 3-Iodobenzoic Acid; 3-(m-Iodophenyl)-3-oxopropionic Acid Ethyl Ester; Ethyl (3-Iodobenzoyl)acetate; 3-(3-Iodophenyl)-3-oxopropionate Ethyl Ester
EINECS	Contact for details

Quality Control

Our 3-(3-Iodo-Phenyl)-3-Oxo-Propionic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.