Description

(2-Chloro-Benzyl)-Trimethyl-Silane is a versatile organosilicon building block characterized by its reactive benzyl chloride and silyl functional groups. This compound is valued for its role in facilitating carbon-silicon bond formation and serving as a protected intermediate in complex synthetic pathways. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing silicon-containing moieties or as a protected synthon.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the chlorobenzyl group is a critical structural element.
• Organometallic Chemistry: Serves as a precursor for generating benzyl anions or other organometallic reagents under mild conditions for cross-coupling reactions.
• Material Science Research: Employed in the development of silicon-based polymers, surface modifiers, and specialty silicones for advanced material properties.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands or modifying catalyst frameworks in asymmetric catalysis and homogeneous catalysis.
• Chemical Derivatization: Acts as a silylating agent or protecting group for alcohols and other sensitive functional groups in multi-step organic synthesis.

Basic Information

Product Name	(2-Chloro-Benzyl)-Trimethyl-Silane
CAS No.	68307-67-5
Molecular Formula	C10H15ClSi
Molecular Weight	198.76 g/mol
Synonyms	1-(Chloromethyl)-2-(trimethylsilyl)benzene; 2-(Trimethylsilylmethyl)chlorobenzene; (2-Chlorophenyl)methyltrimethylsilane; Trimethyl(2-chlorobenzyl)silane; o-Chlorobenzyltrimethylsilane; 2-Chlorobenzyltrimethylsilane; (o-Chlorobenzyl)trimethylsilane; Benzene, 1-(chloromethyl)-2-(trimethylsilyl)-
EINECS	Contact for details

Quality Control

Our (2-Chloro-Benzyl)-Trimethyl-Silane is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.