Description

Ethyl 7-Chloro-2-Methyl-5-Oxo-5H-Chromeno[2,3-B]Pyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel chromenopyridine-based drug candidates with potential therapeutic applications.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to develop new molecules with targeted biological activity.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex heterocyclic compounds in multi-step organic syntheses.
• API Development: Integral to the research and process development stages for new Active Pharmaceutical Ingredients (APIs), particularly in oncology and anti-inflammatory drug discovery.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process scale-up services for the pharmaceutical industry.

Basic Information

Product Name	Ethyl 7-Chloro-2-Methyl-5-Oxo-5H-Chromeno[2,3-B]Pyridine-3-Carboxylate
CAS No.	68301-92-8
Molecular Formula	C₁₆H₁₂ClNO₄
Molecular Weight	317.72 g/mol
Synonyms	7-Chloro-2-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid ethyl ester; Ethyl 7-chloro-2-methyl-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylate; 68301-92-8; Chromeno[2,3-b]pyridine-3-carboxylic acid, 7-chloro-2-methyl-5-oxo-5H-, ethyl ester; Ethyl 7-chloro-2-methyl-5-oxochromeno[2,3-b]pyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for all critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.