Description

8-Bromo-1,4-dioxaspiro[4.5]decane is a versatile brominated spirocyclic ketal, a key protected intermediate in advanced organic synthesis. This compound matters for its role as a crucial building block in the construction of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those containing functionalized cyclohexane or spirocyclic motifs.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where the introduction of a bromine atom is a key synthetic step.
• Fine Chemical Production: Serves as a specialized building block for creating flavors, fragrances, and advanced materials requiring specific brominated structures.
• Academic & Industrial R&D: Employed in methodological chemistry research for developing new synthetic routes and studying reaction mechanisms involving protected carbonyl groups.
• Material Science: Potential use as a monomer or cross-linking agent in the development of specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	8-Bromo-1,4-dioxaspiro[4.5]decane
CAS No.	68278-51-3
Molecular Formula	C8H13BrO2
Molecular Weight	221.09 g/mol
Synonyms	8-Bromospiro[1,3-dioxolane-2,1'-cyclohexane]; 8-Bromo-1,4-dioxaspiro[4.5]decane; 8-Bromocyclohexanone ethylene ketal; 2-(4-Bromobutyl)-1,3-dioxolane; Bromocyclohexanone ethylene ketal; 4-Bromocyclohexanone ethylene ketal; Cyclohexanone, 4-bromo-, ethylene ketal; 1,4-Dioxaspiro[4.5]decane, 8-bromo-
EINECS	Contact for details

Quality Control

Our 8-Bromo-1,4-dioxaspiro[4.5]decane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.