Description

2-Bromo-6-Chlorothieno[2,3-B]Pyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique fused-ring structure, incorporating bromine and chlorine substituents, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive thienopyridine core.
• Material Science: Serves as a building block for organic semiconductors, liquid crystals, and other functional electronic materials.
• Chemical Biology: Employed as a molecular probe or a scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Cross-Coupling Reactions: The bromine and chlorine atoms provide distinct sites for selective palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	2-Bromo-6-Chlorothieno[2,3-B]Pyridine
CAS No.	68236-35-1
Molecular Formula	C7H3BrClNS
Molecular Weight	248.53 g/mol
Synonyms	2-Bromo-6-chlorothieno[2,3-b]pyridine; 6-Chloro-2-bromothieno[2,3-b]pyridine; Thieno[2,3-b]pyridine, 2-bromo-6-chloro-; 68236-35-1; 2-Br-6-Cl-thieno[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Chlorothieno[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures reliable supply for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.