Description

(+)-tert-Butyl D-Lactate is a high-purity chiral building block and protecting group reagent, essential for the synthesis of complex organic molecules. Its primary value lies in providing a sterically hindered, optically pure ester group that enhances reaction selectivity and stability in sensitive synthetic pathways. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as asymmetric synthesis and the production of active pharmaceutical ingredients (APIs).

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key starting material or intermediate for the production of enantiomerically pure drugs and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a chiral auxiliary or reagent to induce stereoselectivity in carbon-carbon bond-forming reactions and other transformations.
• Protecting Group for Carboxylic Acids: The tert-butyl ester group provides temporary protection for carboxylic acid functionalities during multi-step synthetic sequences.
• Agrochemical Research & Development: Employed in the synthesis of novel, optically active herbicides, fungicides, and plant growth regulators.
• Flavor and Fragrance Industry: Serves as a precursor for the synthesis of specific, high-value chiral aroma compounds and flavor ingredients.
• Academic and Industrial R&D: A valuable tool for methodological development in organic chemistry and catalysis research.
• Polymer Chemistry: Can be utilized in the synthesis of chiral monomers for specialty polymers with specific optical or material properties.
• Peptide Chemistry: Used in the synthesis of modified amino acids or peptide fragments where stereochemical integrity is paramount.

Basic Information

Item	Details
Product Name	(+)-tert-Butyl D-Lactate
CAS No.	68166-83-6
Molecular Formula	C7H14O3
Molecular Weight	146.18 g/mol
Synonyms	(R)-(-)-tert-Butyl Lactate; D-(-)-tert-Butyl Lactate; (R)-tert-Butyl 2-Hydroxypropanoate; tert-Butyl (R)-(-)-Lactate; (R)-2-Hydroxypropionic Acid tert-Butyl Ester; (R)-O-tert-Butyl Lactic Acid; (2R)-2-Hydroxypropanoic Acid 1,1-Dimethylethyl Ester
EINECS	Contact for details

Quality Control

Our (+)-tert-Butyl D-Lactate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC or GC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment. We support compliance with cGMP, ISO, and other relevant regulatory frameworks as required for your specific application.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage under an inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 99.0%
Specific Rotation [α]	-15° to -20° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.