Description

Pentaacetyl-α-D-Glucopyranose is a fully acetylated derivative of glucose, serving as a crucial protected intermediate in synthetic organic chemistry. Its primary value lies in providing a stable, non-reactive form of glucose where the hydroxyl groups are masked, enabling selective reactions at other sites or controlled deprotection. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the synthesis of complex carbohydrates, nucleosides, and other glycosylated bioactive molecules.

Application

• Pharmaceutical Intermediate: Key starting material or protected synthon for the production of antiviral drugs, antibiotics, and other glycosylated pharmaceuticals.
• Carbohydrate Chemistry Research: Used in academic and industrial R&D for studying glycosylation reactions, enzyme mechanisms, and synthesizing oligosaccharides.
• Nucleoside & Nucleotide Synthesis: Acts as a glycosyl donor or a protected sugar moiety in the synthesis of modified nucleosides for therapeutic and diagnostic applications.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, fragrances, and advanced materials that require specific sugar derivatives.
• Bioconjugate Chemistry: Useful for creating sugar-protein or sugar-polymer conjugates for vaccine development and targeted drug delivery systems.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Pentaacetyl-α-D-Glucopyranose
CAS No.	68069-84-1
Molecular Formula	C16H22O11
Molecular Weight	390.34 g/mol
Synonyms	1,2,3,4,6-Penta-O-acetyl-α-D-glucopyranose; α-D-Glucopyranose, 1,2,3,4,6-pentaacetate; Penta-O-acetyl-α-D-glucopyranose; Pentaacetyl-α-D-glucose; α-Acetobromoglucose precursor; Acetylated α-D-glucose; 1,2,3,4,6-Pentaacetyl-α-D-glucose
EINECS	Contact for details

Quality Control

Our Pentaacetyl-α-D-Glucopyranose is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and optical rotation measurement, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP and ISO standards for pharmaceutical and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent hydrolysis and maintain stability. The storage area should be well-ventilated and away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	+98° to +102° (c=1 in CHCl3)
Melting Point	110°C - 113°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.