Description

3,3'-Dioctadecyloxacarbocyanine is a lipophilic, cationic cyanine dye widely used as a fluorescent probe for membrane labeling and biophysical studies. Its core value lies in its high affinity for lipid bilayers, enabling sensitive visualization and quantification of cellular membranes, vesicles, and lipoproteins. This product is essential for researchers and manufacturers in the life sciences, particularly for applications in cell biology, neuroscience, and the development of diagnostic assays and drug delivery systems.

Application

• Fluorescent Cell Membrane Staining: Selective labeling of plasma and intracellular membranes for live-cell and fixed-cell imaging.
• Lipid Vesicle & Lipoprotein Tracking: Visualization and characterization of synthetic liposomes, exosomes, and LDL/HDL particles in research.
• Mitochondrial Membrane Potential Assays: Use as a potentiometric dye to monitor mitochondrial health and function in cell-based assays.
• Neuronal and Axonal Tracing: Long-term tracking of neuronal processes due to stable incorporation into membranes.
• Flow Cytometry: Detection and analysis of specific cell populations based on membrane characteristics.
• Model Membrane Studies: Investigation of lipid dynamics, phase separation, and membrane fusion in artificial bilayer systems.
• Drug Delivery Research: Labeling of lipid-based nanocarriers to study their biodistribution and cellular uptake.

Basic Information

Product Name	3,3'-Dioctadecyloxacarbocyanine
CAS No.	68006-80-4
Molecular Formula	C59H91N2O+
Molecular Weight	836.4 g/mol
Synonyms	DiOC18(3); 3,3'-Dioctadecyloxacarbocyanine perchlorate; DiI; Dioctadecyloxacarbocyanine; DiIC18(3); D-275; D-3883; Lipophilic Tracer DiI; 1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate (common misnomer, structurally related)
EINECS	Contact for details

Quality Control

Our 3,3'-Dioctadecyloxacarbocyanine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for identity confirmation, to ensure consistent performance and high batch-to-batch reproducibility. Certificates of Analysis (COA) detailing purity, absorbance/fluorescence profiles, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant for long-term stability. Allow the product to equilibrate to room temperature before opening to prevent condensation. The material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Dark green to purple solid or crystalline powder
Identification (HPLC/UV-Vis)	Conforms to reference standard
Purity (HPLC)	≥ 95% (typical)
Absorption Max (λmax)	~549 nm (in methanol)
Emission Max (λem)	~565 nm (in methanol)
Extinction Coefficient (ε)	Contact for details
Solubility	Soluble in DMSO, DMF, ethanol, methanol; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.