Description

(4-Bromophenoxy)-tert-Butyldimethylsilane is a high-purity organosilicon reagent featuring a bromophenoxy moiety protected by a tert-butyldimethylsilyl (TBDMS) group. This compound is a critical synthetic intermediate, valued for its role in constructing complex molecules where selective deprotection and functionalization are required. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of active ingredients and novel organic frameworks.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring phenol protection strategies.
• Agrochemical Synthesis: Used in the research and development of herbicides, fungicides, and other crop protection agents.
• Liquid Crystal & OLED Materials: Serves as a precursor in the creation of advanced organic electronic materials and liquid crystal displays.
• Polymer & Resin Modification: Employed to introduce bromophenoxy functional groups into polymer chains for specialty resins and coatings.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions like Suzuki, Heck, or Sonogashira couplings for carbon-carbon bond formation.
• Organic Synthesis Research: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and protecting group chemistry.

Basic Information

Product Name	(4-Bromophenoxy)-tert-Butyldimethylsilane
CAS No.	67963-68-2
Molecular Formula	C₁₂H₁₉BrOSi
Molecular Weight	287.27 g/mol
Synonyms	4-Bromophenoxy-tert-butyldimethylsilane; tert-Butyl(4-bromophenoxy)dimethylsilane; 1-Bromo-4-[(tert-butyldimethylsilyl)oxy]benzene; 4-Bromophenyl tert-butyldimethylsilyl ether; TBDMS 4-bromophenyl ether; 4-BrPhOTBDMS; (p-Bromophenoxy)dimethyl-tert-butylsilane; Silane, (4-bromophenoxy)-tert-butyldimethyl-
EINECS	Contact for details

Quality Control

Every batch of (4-Bromophenoxy)-tert-Butyldimethylsilane is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.