Description

3-Hydroxy-2-(Hydroxymethyl)-2-Methyl-Propanoic Acid, Isobenzofuran-1,3 -Dione is a specialized organic compound that serves as a key multifunctional building block in advanced chemical synthesis. Its unique structure, featuring both carboxylic acid and hydroxyl groups fused with a phthalic anhydride moiety, makes it valuable for creating polymers, resins, and fine chemicals with tailored properties. This intermediate is particularly relevant for manufacturers in the pharmaceutical, agrochemical, and high-performance polymer industries seeking to develop novel materials and active ingredients.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, leveraging its reactive sites for conjugation.
• Polymer & Resin Modifier: Acts as a cross-linking agent or monomer to enhance the thermal stability, adhesion, and mechanical properties of polyesters, alkyd resins, and epoxy systems.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and specialty chemicals requiring complex carboxylic acid derivatives.
• Adhesive & Coating Formulations: Improves performance characteristics in industrial coatings, inks, and adhesive compositions.
• Research & Development: A valuable reagent in organic chemistry R&D for constructing complex molecular architectures.

Basic Information

Product Name	3-Hydroxy-2-(Hydroxymethyl)-2-Methyl-Propanoic Acid, Isobenzofuran-1,3 -Dione
CAS No.	67953-40-6
Molecular Formula	C12H12O6
Molecular Weight	252.22 g/mol
Synonyms	2-(Hydroxymethyl)-2-methyl-3-hydroxypropanoic acid phthalic anhydride adduct; 3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoic acid 1,3-dihydro-1,3-dioxoisobenzofuran-5-carboxylate; Bis(hydroxymethyl)methylglycolic acid phthalic anhydride ester; Phthalic anhydride monoester of 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoic acid; Trimethylolacetic acid phthalic anhydride monoester; THPA-TMA adduct; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our production of 3-Hydroxy-2-(Hydroxymethyl)-2-Methyl-Propanoic Acid, Isobenzofuran-1,3 -Dione adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency meet the high standards required for industrial and research applications. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay, impurity profile, and physical characteristics is provided with each shipment to guarantee supply reliability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.