Description

2-(n-Boc-Aminomethyl)-5-Chloropyridine is a high-purity, protected amine building block essential for advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, particularly those containing pyridine and amine pharmacophores.
• Peptidomimetic Research: Used to introduce protected aminoalkyl side chains into heterocyclic scaffolds for the development of protease inhibitors and receptor modulators.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and insecticides with specific activity profiles.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create tagged or functionalized molecules for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	2-(n-Boc-Aminomethyl)-5-Chloropyridine
CAS No.	67938-77-6
Molecular Formula	C11H15ClN2O2
Molecular Weight	242.70 g/mol
Synonyms	5-Chloro-2-((tert-butoxycarbonylamino)methyl)pyridine; 2-((tert-Butoxycarbonylamino)methyl)-5-chloropyridine; 2-(Boc-Aminomethyl)-5-chloropyridine; tert-Butyl N-[(5-chloropyridin-2-yl)methyl]carbamate; 5-Chloro-2-pyridinemethanamine, N-BOC-; Boc-AMC-Pyridine; N-Boc-5-chloro-2-aminomethylpyridine
EINECS	Contact for details

Quality Control

Every batch of 2-(n-Boc-Aminomethyl)-5-Chloropyridine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.