Description

1-(5-Chloropyridin-2-Yl)Methanamine is a versatile pyridine derivative building block of significant importance in advanced organic synthesis. Its core value lies in its functionalized structure, which serves as a key intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the chloropyridine moiety for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis for coupling reactions.
• Material Science Research: Employed in the creation of functionalized polymers and organic electronic materials due to its aromatic amine structure.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Bioconjugation and Probe Development: The reactive amine group allows for conjugation chemistry, useful in developing biochemical probes and diagnostic agents.

Basic Information

Product Name	1-(5-Chloropyridin-2-Yl)Methanamine
CAS No.	67938-76-5
Molecular Formula	C6H7ClN2
Molecular Weight	142.59 g/mol
Synonyms	(5-Chloro-2-pyridinyl)methanamine; 2-(Aminomethyl)-5-chloropyridine; 5-Chloro-2-pyridinemethanamine; 1-(5-Chloro-2-pyridinyl)methanamine; 5-Chloro-2-(aminomethyl)pyridine; (5-Chloropyridin-2-yl)methylamine; 2-Aminomethyl-5-chloropyridine
EINECS	Contact for details

Quality Control

Our 1-(5-Chloropyridin-2-Yl)Methanamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.