Description

1-Naphthyl 5-Oxo-L-Prolinate is a specialized chiral building block and a derivative of the amino acid L-proline. This compound is valued for its role in the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily utilized by research institutions and chemical companies engaged in developing new active pharmaceutical ingredients (APIs), catalysts, and advanced organic materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including enzyme inhibitors and receptor modulators.
• Asymmetric Catalysis: Serves as a precursor for ligands or catalysts used in stereoselective synthesis to produce enantiomerically pure compounds.
• Peptidomimetics Research: Used in the design and synthesis of peptide analogs and constrained proline derivatives for biochemical studies.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	1-Naphthyl 5-Oxo-L-Prolinate
CAS No.	67934-90-1
Molecular Formula	C₁₅H₁₅NO₃
Molecular Weight	257.29 g/mol
Synonyms	L-Proline, 5-oxo-, 1-naphthyl ester; (S)-1-Naphthyl 5-oxopyrrolidine-2-carboxylate; 5-Oxo-L-proline 1-naphthyl ester; 1-Naphthyl (S)-5-oxopyrrolidine-2-carboxylate; 1-Naphthyl 5-oxo-L-prolinate; 1-Naphthyl pyrrolidonecarboxylate; 1-Naphthyl ester of 5-oxo-L-proline
EINECS	Contact for details

Quality Control

Our 1-Naphthyl 5-Oxo-L-Prolinate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and synthesis applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.