Description

(4R,5R)-5-(Methoxycarbonyl)-2,2-Dimethyl-1,3-Dioxolane-4-Carboxylic Acid is a high-value chiral building block and protected derivative of tartaric acid. This compound matters for its role as a key intermediate in the stereoselective synthesis of complex pharmaceutical molecules and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of protease inhibitors, antiviral drugs, and other active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to construct complex molecules with high enantiomeric purity.
• Agrochemical Synthesis: Serves as a building block for creating chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, fragrances, and advanced polymers where precise molecular architecture is required.
• Academic & R&D: A valuable reagent in laboratory-scale research for method development and exploring new synthetic pathways in organic chemistry.
• Peptidomimetics: Used in the construction of peptide analogs and mimetics due to its carboxylic acid and ester functional groups within a rigid, protected diol framework.

Basic Information

Product Name	(4R,5R)-5-(Methoxycarbonyl)-2,2-Dimethyl-1,3-Dioxolane-4-Carboxylic Acid
CAS No.	67812-33-3
Molecular Formula	C9H14O6
Molecular Weight	218.21 g/mol
Synonyms	(4R,5R)-2,2-Dimethyl-1,3-dioxolane-4,5-dicarboxylic acid 5-methyl ester; (4R,5R)-5-(Methoxycarbonyl)-2,2-dimethyl-1,3-dioxolane-4-carboxylic acid; (4R,5R)-Dimethyl tartrate acetonide; L-(+)-Dimethyl Tartrate Acetonide; (4R,5R)-2,2-Dimethyl-1,3-dioxolane-4,5-dicarboxylic Acid 5-Methyl Ester; (R,R)-Dimethyl Tartrate Acetonide; Acetonide of Dimethyl L-Tartrate
EINECS	Contact for details

Quality Control

Our (4R,5R)-5-(Methoxycarbonyl)-2,2-Dimethyl-1,3-Dioxolane-4-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.