Description

Boc-Abu-Onp CAS NO 67708-97-8 is a specialized amino acid derivative, specifically the p-nitrophenyl ester of N-Boc-2-aminobutyric acid, designed for efficient peptide synthesis. This compound serves as a crucial activated building block, enabling controlled coupling reactions to construct complex peptide chains with high fidelity. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for the development of novel therapeutic peptides and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an activated ester for the controlled incorporation of 2-aminobutyric acid (Abu) under mild conditions.
• Solution-Phase Peptide Coupling: Facilitating the synthesis of specific peptide fragments and conjugates in solution.
• Pharmaceutical Intermediate: A key precursor in the research and development of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Used for labeling proteins or other biomolecules with Abu-containing tags or linkers.
• Chemical Biology Research: Employed in the study of protein-protein interactions and the creation of peptide libraries for screening.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group allows for orthogonal deprotection schemes in complex multi-step syntheses.

Basic Information

Product Name	Boc-Abu-Onp
CAS No.	67708-97-8
Molecular Formula	C₁₅H₂₀N₂O₆
Molecular Weight	324.33 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-2-aminobutyric acid 4-nitrophenyl ester; Boc-2-Abu-ONp; Boc-Abu-ONp; N-Boc-2-aminobutyric acid p-nitrophenyl ester; (S)-2-((tert-Butoxycarbonyl)amino)butanoic acid 4-nitrophenyl ester; tert-Butyl (1-((4-nitrophenoxy)oxy)-1-oxobutan-2-yl)carbamate; Boc-L-2-aminobutyric acid 4-nitrophenyl ester
EINECS	Contact for details

Quality Control

Our Boc-Abu-Onp is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.