Description

Methyl (R)-3-Acetamido-3-Phenylpropanoate is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound is valued for its role as a key building block in the production of optically active pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing enantiomerically pure active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Used as a starting material or building block in stereoselective reactions, including hydrogenations and cross-couplings, to construct complex molecular architectures.
• Agrochemical Research: Serves as a precursor in the development of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Catalyst & Ligand Development: Employed in the research and preparation of novel chiral catalysts and ligands for homogeneous catalysis.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Process R&D: A valuable compound for methodological studies in organic chemistry and for scaling up synthetic routes in process chemistry.

Basic Information

Product Name	Methyl (R)-3-Acetamido-3-Phenylpropanoate
CAS No.	67654-57-3
Molecular Formula	C12H15NO3
Molecular Weight	221.25 g/mol
Synonyms	(R)-Methyl 3-Acetamido-3-phenylpropanoate; (R)-3-Acetamido-3-phenylpropionic Acid Methyl Ester; Methyl (R)-3-Acetylamino-3-phenylpropionate; (R)-3-Acetamido-3-phenylpropanoic Acid Methyl Ester; (R)-Methyl 3-Acetylamino-3-phenylpropanoate; (R)-3-Phenyl-3-acetamidopropionic Acid Methyl Ester; (R)-β-Acetamidohydrocinnamic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl (R)-3-Acetamido-3-Phenylpropanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.