Description

7-(3-Hydroxypropyl)-2-Methyl-4-Oxo-4,7-Dihydrothieno[2,3-B]Pyridine-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the creation of new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug molecules, particularly those targeting specific enzymatic pathways.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the development of new APIs, especially in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Biochemical Research: Used as a standard or reagent in biochemical assays and pharmacological studies to investigate structure-activity relationships (SAR).
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for constructing complex heterocyclic systems found in agrochemicals and specialty chemicals.
• Contract Manufacturing (CMO/CDMO): Supplied to contract manufacturing organizations for use in custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Product Name	7-(3-Hydroxypropyl)-2-Methyl-4-Oxo-4,7-Dihydrothieno[2,3-B]Pyridine-5-Carboxylic Acid
CAS No.	67637-77-8
Molecular Formula	C₁₃H₁₃NO₄S
Molecular Weight	279.31 g/mol
Synonyms	Thieno[2,3-b]pyridine-5-carboxylic acid, 4,7-dihydro-7-(3-hydroxypropyl)-2-methyl-4-oxo-; 7-(3-Hydroxypropyl)-2-methyl-4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxylic acid; 4,7-Dihydro-7-(3-hydroxypropyl)-2-methyl-4-oxothieno[2,3-b]pyridine-5-carboxylic acid; 67637-77-8; Thienopyridine carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 7-(3-Hydroxypropyl)-2-Methyl-4-Oxo-4,7-Dihydrothieno[2,3-B]Pyridine-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.