Description

7-(3-Carboxypropyl)-2-Methyl-4-Oxo-4,7-Dihydrothieno[2,3-B]Pyridine-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting specific enzymatic pathways.
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new chemical entities with potential biological activity.
• API Synthesis: Serves as a core scaffold or building block in multi-step synthetic routes for Active Pharmaceutical Ingredients.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high-purity, structurally defined intermediates.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Bioconjugation Chemistry: The carboxylic acid groups offer handles for conjugation, useful in developing prodrugs or targeted therapies.

Basic Information

Product Name	7-(3-Carboxypropyl)-2-Methyl-4-Oxo-4,7-Dihydrothieno[2,3-B]Pyridine-5-Carboxylic Acid
CAS No.	67637-76-7
Molecular Formula	C14H13NO5S
Molecular Weight	307.32 g/mol
Synonyms	2-Methyl-4-oxo-7-(3-carboxypropyl)-4,7-dihydrothieno[2,3-b]pyridine-5-carboxylic acid; Thieno[2,3-b]pyridine-5-carboxylic acid, 4,7-dihydro-7-(3-carboxypropyl)-2-methyl-4-oxo-; 7-(3-Carboxypropyl)-2-methyl-4-oxo-4H,7H-thieno[2,3-b]pyran-5-carboxylic acid (related form); 67637-76-7; Advanced thienopyridine intermediate; Pharmaceutical building block 67637-76-7
EINECS	Contact for details

Quality Control

Our production of 7-(3-Carboxypropyl)-2-Methyl-4-Oxo-4,7-Dihydrothieno[2,3-B]Pyridine-5-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet the requirements of cGMP, ICH guidelines, and other relevant pharmaceutical standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.