Description

(S)-Ethyl 2-(tert-Butoxycarbonylamino)-3-(4-Nitrophenyl)Propanoate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptidomimetics, protease inhibitors, and other bioactive molecules.
• Asymmetric Synthesis: Used as a starting material or building block for constructing complex, enantiomerically pure compounds in medicinal chemistry research.
• API Development: Serves as a precursor in the research and scale-up production of novel Active Pharmaceutical Ingredients (APIs).
• Peptide Chemistry: Employed in the preparation of non-natural amino acid derivatives and peptide analogs for drug discovery.
• Agrochemical Research: Utilized in the development of chiral active ingredients for crop protection products.
• Academic & Industrial R&D: A valuable reagent for method development and synthetic route exploration in organic chemistry laboratories.

Basic Information

Product Name	(S)-Ethyl 2-(tert-Butoxycarbonylamino)-3-(4-Nitrophenyl)Propanoate
CAS No.	67630-00-6
Molecular Formula	C₁₆H₂₂N₂O₆
Molecular Weight	338.36 g/mol
Synonyms	(S)-Ethyl 2-((tert-Butoxycarbonyl)amino)-3-(4-nitrophenyl)propanoate; Boc-L-4-Nitrophenylalanine Ethyl Ester; (S)-2-(Boc-amino)-3-(4-nitrophenyl)propionic Acid Ethyl Ester; N-Boc-4-Nitro-L-phenylalanine Ethyl Ester; N-α-Boc-4-nitro-L-phenylalanine ethyl ester; Ethyl (2S)-2-[(tert-butoxycarbonyl)amino]-3-(4-nitrophenyl)propanoate; (S)-Ethyl 3-(4-nitrophenyl)-2-((tert-butoxycarbonyl)amino)propanoate; L-4-Nitrophenylalanine, N-Boc-, ethyl ester
EINECS	Contact for details

Quality Control

Our (S)-Ethyl 2-(tert-Butoxycarbonylamino)-3-(4-Nitrophenyl)Propanoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry standards and can provide material for GMP applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.