Description

Spiro[Bicyclo[2.2.1]Heptane-2,2’-[1,3]Dioxolan]-5-One is a high-value, synthetically versatile spirocyclic compound characterized by its unique fused bicyclic and dioxolane structure. This compound serves as a critical advanced pharmaceutical intermediate (API) and a sophisticated building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used as a building block for developing novel pesticides and herbicides with specific stereochemical activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing spirocyclic and bridged ring systems prevalent in natural products.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal or mechanical properties.
• Catalyst & Ligand Development: Serves as a scaffold for designing novel chiral ligands used in asymmetric catalysis.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing complex odorants and flavor compounds with specific stereocenters.

Basic Information

Product Name	Spiro[Bicyclo[2.2.1]Heptane-2,2’-[1,3]Dioxolan]-5-One
CAS No.	67594-61-0
Molecular Formula	C9H12O3
Molecular Weight	168.19 g/mol
Synonyms	5-Oxaspiro[bicyclo[2.2.1]heptane-2,2'-[1,3]dioxolane]; 2,4-Dioxaspiro[bicyclo[2.2.1]heptane-5,2'-[1,3]dioxolane]; Spiro(bicyclo[2.2.1]heptane-2,2'-[1,3]dioxolan)-5-one; 5-Oxaspiro[bicyclo[2.2.1]heptane-2,2'-[1,3]dioxolan]; Bicyclo[2.2.1]heptane-2-spiro-2'-[1,3]dioxolan]-5-one
EINECS	Contact for details

Quality Control

Our Spiro[Bicyclo[2.2.1]Heptane-2,2’-[1,3]Dioxolan]-5-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.