Description

5-(Trimethylsilyl)Quinoline is a versatile organosilicon compound featuring a quinoline core functionalized with a trimethylsilyl group. This modification imparts unique steric and electronic properties, making it a valuable intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and functional materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing quinoline or complex heterocyclic frameworks.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of organic semiconductors, liquid crystals, and advanced polymers.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic systems.
• Organic Synthesis Reagent: Utilized as a protecting group or as a reactant in cross-coupling reactions and other metal-catalyzed transformations.
• Research & Development: Essential compound in academic and industrial laboratories for exploring new synthetic methodologies and chemical spaces.

Basic Information

Product Name	5-(Trimethylsilyl)Quinoline
CAS No.	67532-97-2
Molecular Formula	C₁₂H₁₅NSi
Molecular Weight	201.34 g/mol
Synonyms	5-(Trimethylsilyl)quinoline; Quinoline, 5-(trimethylsilyl)-; 5-TMS-Quinoline; 5-(Trimethylsilyl)chinolin; 5-Trimethylsilylquinoline; 5-Quinolyltrimethylsilane; 5-(TMS)Quinoline
EINECS	Contact for details

Quality Control

Our 5-(Trimethylsilyl)Quinoline is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.