Description

2-Isocyano-4-Methylpentanoic Acid Methyl Ester is a versatile isocyanide building block used in multicomponent reactions and heterocyclic synthesis. This compound is valued for its role in facilitating the efficient construction of complex molecular scaffolds, including natural product analogs and pharmaceutical intermediates. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for lead optimization and novel compound library generation.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of heterocyclic compounds and peptidomimetics via Passerini and Ugi multicomponent reactions.
• Agrochemical Research: Used in the development of novel active ingredients and fungicides by constructing diverse chemical libraries.
• Material Science: Serves as a building block for functionalized polymers and ligands for catalysis.
• Academic & R&D: Essential for methodological development in organic synthesis and medicinal chemistry research programs.
• Peptide Chemistry: Employed in the synthesis of isocyanopeptides and other modified peptide structures.

Basic Information

Product Name	2-Isocyano-4-Methylpentanoic Acid Methyl Ester
CAS No.	67524-41-8
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	Methyl 2-Isocyano-4-methylpentanoate; 4-Methyl-2-isocyanopentanoic Acid Methyl Ester; Methyl 4-Methyl-2-isocyanovalerate; 2-Isocyano-4-methylvaleric Acid Methyl Ester; Leucine Isocyanide Methyl Ester; Isocyano-leucine Methyl Ester
EINECS	Contact for details

Quality Control

Our 2-Isocyano-4-Methylpentanoic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.