Description

Ethyl 4-Fluoro-3-(Trifluoromethyl)Benzoate is a high-value fluorinated aromatic ester, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is engineered to impart desirable properties such as enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine motifs contribute to improved biological activity and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs) due to its ability to modify dielectric anisotropy and viscosity.
• Organic Electronics: Employed in the development of novel organic semiconductors and electron-transport materials for OLEDs and photovoltaic cells.
• Advanced Polymer Modifiers: Incorporated as a monomer or additive to create specialty polymers with enhanced chemical resistance, thermal stability, and surface properties.
• Chemical Research & Development: A versatile reagent for introducing the 4-fluoro-3-(trifluoromethyl)benzoyl moiety into complex molecules via esterification, hydrolysis, or cross-coupling reactions.

Basic Information

Item	Detail
Product Name	Ethyl 4-Fluoro-3-(Trifluoromethyl)Benzoate
CAS No.	67515-63-3
Molecular Formula	C10H8F4O2
Molecular Weight	236.16 g/mol
Synonyms	Ethyl 4-Fluoro-α,α,α-trifluoro-m-toluate; Benzoic acid, 4-fluoro-3-(trifluoromethyl)-, ethyl ester; 4-Fluoro-3-trifluoromethylbenzoic Acid Ethyl Ester; Ethyl 4-Fluoro-3-trifluoromethylbenzoate; m-Trifluoromethyl-p-fluorobenzoic Acid Ethyl Ester; Ethyl 4-Fluoro-3-(trifluoromethyl)benzoate; Ethyl 4-Fluoro-α,α,α-trifluoro-m-toluate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Fluoro-3-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.