Description

10-(3-Dimethylamino-2-Methylpropyl)-10H-Pyrido[3,2-B][1,4]Benzothiazine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, where precise chemical structure and high purity are non-negotiable for successful drug development and regulatory approval.

Application

• Key Intermediate in CNS Drug Synthesis: Serves as a crucial building block for the research and production of potential antipsychotic and neuroleptic pharmaceutical compounds.
• Pharmacological Research: Used in academic and industrial R&D laboratories for studying structure-activity relationships (SAR) and developing new chemical entities (NCEs).
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: Acts as a starting material for the custom synthesis of more complex, target-specific molecules for preclinical studies.

Basic Information

Product Name	10-(3-Dimethylamino-2-Methylpropyl)-10H-Pyrido[3,2-B][1,4]Benzothiazine
CAS No.	67465-70-7
Molecular Formula	C₁₇H₂₁N₃S
Molecular Weight	299.43 g/mol
Synonyms	10-(3-Dimethylamino-2-methylpropyl)-10H-pyrido[3,2-b][1,4]benzothiazine; 10H-Pyrido[3,2-b][1,4]benzothiazine, 10-[3-(dimethylamino)-2-methylpropyl]-; Perlapine intermediate; Potential antipsychotic intermediate; CAS 67465-70-7
EINECS	Contact for details

Quality Control

Our production of 10-(3-Dimethylamino-2-Methylpropyl)-10H-Pyrido[3,2-B][1,4]Benzothiazine adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research and development work. Each lot is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.