Description

(S)-2-Aziridinecarboxylic Acid Benzyl Ester is a high-purity chiral aziridine derivative, a crucial building block in asymmetric synthesis. Its value lies in providing a protected, enantiomerically pure aziridine-2-carboxylate scaffold, enabling the stereoselective introduction of nitrogen-containing functional groups. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of β-amino acids, amino alcohols, and nitrogen heterocycles found in drug candidates.
• Asymmetric Synthesis: Used in ring-opening reactions with nucleophiles to create chiral diamines and other complex molecules with high enantiomeric excess.
• Peptidomimetics Research: Serves as a constrained analog in the design and synthesis of peptide mimics to modulate biological activity and stability.
• Agrochemical Development: Building block for creating chiral herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Precursor for nitrogen-donor ligands used in asymmetric catalysis.
• Academic & R&D Laboratories: Fundamental reagent for methodological studies in organic and medicinal chemistry.

Basic Information

Item	Detail
Product Name	(S)-2-Aziridinecarboxylic Acid Benzyl Ester
CAS No.	67413-26-7
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	(S)-(-)-1-Benzyl 2-Aziridinecarboxylate; (S)-Benzyl Aziridine-2-carboxylate; (S)-Benzyl 2-Aziridinecarboxylate; L-Aziridine-2-carboxylic Acid Benzyl Ester; (-)-(S)-Benzyl Aziridine-2-carboxylate; Benzyl (S)-aziridine-2-carboxylate; Aziridine-2-carboxylic acid, benzyl ester, (2S)-
EINECS	Contact for details

Quality Control

Every batch of our (S)-2-Aziridinecarboxylic Acid Benzyl Ester is produced and tested under strict quality management systems. We ensure high enantiomeric purity and chemical integrity through advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing chiral purity, chemical purity, and identity is provided with each shipment, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This moisture-sensitive compound should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.