Description

Pyrimethamine 3-n-Oxide CAS NO 67412-31-1 is a key chemical intermediate and derivative of the established antiparasitic agent pyrimethamine. This compound is of significant interest in pharmaceutical research and development, particularly for the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new drug candidates and specialized formulations.

Application

• Pharmaceutical Intermediate: A crucial building block in the research and synthesis of new antiparasitic and antimicrobial drug candidates.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor or derivative in the development of APIs targeting specific diseases.
• Biochemical Research: Used as a reference standard or probe in studies investigating enzyme inhibition and metabolic pathways.
• Agrochemical Research: Investigated for potential applications in the development of novel crop protection agents.
• Veterinary Medicine: Explored for use in formulations aimed at treating parasitic infections in animals.

Basic Information

Product Name	Pyrimethamine 3-n-Oxide
CAS No.	67412-31-1
Molecular Formula	C12H13ClN4O2
Molecular Weight	280.71 g/mol
Synonyms	5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine 3-oxide; Pyrimethamine N-oxide; 2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine 3-oxide; 6-Ethyl-5-(4-chlorophenyl)-2,4-pyrimidinediamine 1-oxide; Daraprim N-oxide; Pyrimethamine 1-oxide; 5-(4-Chlorophenyl)-6-ethylpyrimidine-2,4-diamine 3-oxide
EINECS	Contact for details

Quality Control

Our Pyrimethamine 3-n-Oxide is produced and tested under a rigorous quality management system. Each batch undergoes comprehensive analysis to ensure identity, purity, and consistency, meeting the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.