Description

4,4'-Peroxybis[2-[Bis(2-Chloroethyl)Amino]Tetrahydro-2H-1,3,2-Oxazaphosphorine] is a specialized organophosphorus compound containing a peroxide linkage and nitrogen mustard functionalities. This unique structure makes it a valuable intermediate for advanced chemical synthesis, particularly in the development of novel pharmaceutical agents and research chemicals. It is primarily sought by R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted bioactive molecules. The compound is supplied with a CAS number of 67292-65-3.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of novel chemotherapeutic agents and targeted therapies.
• Chemical Research: Used in academic and industrial laboratories for studying structure-activity relationships (SAR) of nitrogen mustard derivatives.
• Advanced Organic Synthesis: Serves as a specialized precursor for constructing complex molecules with peroxide and phosphoramide groups.
• Bioconjugation Studies: Potential use in developing prodrugs or antibody-drug conjugates (ADCs) due to its reactive chloroethyl groups.
• Polymer Chemistry: Can be investigated as a cross-linking agent or initiator for specialty polymer formulations.

Basic Information

Product Name	4,4'-Peroxybis[2-[Bis(2-Chloroethyl)Amino]Tetrahydro-2H-1,3,2-Oxazaphosphorine]
CAS No.	67292-65-3
Molecular Formula	C₁₆H₃₂Cl₄N₄O₆P₂
Molecular Weight	580.22 g/mol
Synonyms	4,4'-Dioxo-bis(2-[bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine); Bis(2-[bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine) Peroxide; 2,2'-(Peroxydicarbonyl)bis[2-[bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide]; NSC 178248; Oxazaphosphorine Peroxide Derivative
EINECS	Contact for details

Quality Control

Our 4,4'-Peroxybis[2-[Bis(2-Chloroethyl)Amino]Tetrahydro-2H-1,3,2-Oxazaphosphorine] is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.