Description

3-(Pyrrolidin-2-Yl)Pyridine Dihydrochloride is a high-purity, pharmaceutically relevant organic salt, serving as a critical building block in modern medicinal chemistry. Its value lies in its unique pyrrolidine-pyridine hybrid structure, which is a privileged scaffold for designing bioactive molecules targeting the central nervous system. This compound is essential for research and development chemists in the pharmaceutical and biotechnology sectors, particularly those focused on synthesizing novel drug candidates for neurological and psychiatric disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent and selective nicotinic acetylcholine receptor (nAChR) modulators and other neuroactive compounds.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency, selectivity, and pharmacokinetic properties.
• Ligand Synthesis: Employed in the development of novel ligands for neurological targets, contributing to research in areas like cognitive enhancement and addiction treatment.
• Chemical Biology Probes: Serves as a core structure for creating molecular probes to study receptor function and signaling pathways in the brain.
• Process Chemistry Development: Used in scaling up synthetic routes for active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) guidelines.
• Academic & Institutional R&D: A valuable reagent for universities and research institutes conducting cutting-edge neuroscience and drug discovery projects.

Basic Information

Product Name	3-(Pyrrolidin-2-Yl)Pyridine Dihydrochloride
CAS No.	67209-89-6
Molecular Formula	C9H14N2·2HCl
Molecular Weight	231.14 g/mol
Synonyms	2-(3-Pyridinyl)pyrrolidine dihydrochloride; 3-(2-Pyrrolidinyl)pyridine dihydrochloride; Noranabasine dihydrochloride; 3-Pyrrolidin-2-ylpyridine dihydrochloride; 2-(Pyridin-3-yl)pyrrolidine dihydrochloride; (RS)-3-(2-Pyrrolidinyl)pyridine dihydrochloride; 3-Pyridylpyrrolidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 3-(Pyrrolidin-2-Yl)Pyridine Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for advanced research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material produced under current Good Manufacturing Practice (cGMP) guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.