Description

11-Isopropyl-2,4-diazaspiro[5.5]undec-8-ene-1,3,5-trione is a specialized spirocyclic hydantoin derivative, a high-value synthetic intermediate prized for its unique constrained molecular architecture. This compound matters for its role as a critical building block in advanced pharmaceutical and agrochemical research, enabling the development of novel active ingredients with targeted properties. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries seeking to incorporate complex, three-dimensional scaffolds into their molecular designs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring spirocyclic motifs for enhanced bioavailability and metabolic stability.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or insecticides where the spirocyclic structure can impart unique modes of action and selectivity.
• Ligand & Catalyst Development: Acts as a sophisticated ligand precursor or core structure for asymmetric catalysis in complex organic transformations.
• Material Science: Potential building block for advanced polymers or organic electronic materials requiring rigid, heterocyclic components.
• Chemical Biology Probe: Utilized in medicinal chemistry to create tool compounds for probing enzyme active sites or protein-protein interactions due to its defined three-dimensional shape.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic routes requiring high-purity advanced intermediates.

Basic Information

Product Name	11-Isopropyl-2,4-diazaspiro[5.5]undec-8-ene-1,3,5-trione
CAS No.	67196-38-7
Molecular Formula	C12H16N2O3
Molecular Weight	236.27 g/mol
Synonyms	11-Isopropyl-2,4-diazaspiro[5.5]undec-8-ene-1,3,5-trione; 2,4-Diazaspiro[5.5]undec-8-ene-1,3,5-trione, 11-isopropyl-; 11-Isopropyl-2,4-diazaspiro[5.5]undec-8-ene-1,3,5-trione; Spirocyclic hydantoin derivative; 11-Isopropyl-spiro-hydantoin; CAS 67196-38-7
EINECS	Contact for details

Quality Control

Our 11-Isopropyl-2,4-diazaspiro[5.5]undec-8-ene-1,3,5-trione is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.