Description

5-Fluoro-2-Methylphenyl Isocyanate is a specialized aromatic isocyanate monomer used as a key building block in the synthesis of advanced chemical products. This compound is valued for its ability to introduce both fluorine and isocyanate functional groups, enabling the creation of materials with enhanced properties such as chemical resistance, thermal stability, and specific biological activity. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel active ingredients and high-performance resins.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides where the fluorine moiety improves bioavailability and environmental stability.
• Polymer & Resin Modification: Serves as a monomer for producing polyurethanes and polyurea coatings with enhanced weatherability, chemical resistance, and adhesion properties.
• Chemical Research & Development: Employed in academic and industrial labs for creating novel heterocyclic compounds and exploring structure-activity relationships (SAR).
• Liquid Crystal & Electronic Materials: A building block for advanced materials used in display technologies and organic semiconductors.

Basic Information

Product Name	5-Fluoro-2-Methylphenyl Isocyanate
CAS No.	67191-93-9
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	2-Methyl-5-fluorophenyl isocyanate; 5-Fluoro-o-tolyl isocyanate; 1-Fluoro-2-isocyanato-4-methylbenzene; Isocyanic acid, 5-fluoro-2-methylphenyl ester; 5-Fluoro-2-methylbenzenisocyanate; 2-Fluoro-5-isocyanatotoluene
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methylphenyl Isocyanate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and light-sensitive nature. Keep away from heat, open flames, and incompatible materials such as alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.