Description

4-(tert-Butyl)Picolinaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of a reactive aldehyde group and a sterically hindered tert-butyl substituent on the pyridine ring, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require sophisticated intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in creating complex heterocyclic cores for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the pyridine moiety contributes to biological activity.
• Ligand and Catalyst Development: Employed in the preparation of specialized nitrogen-containing ligands for transition metal catalysis, useful in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of novel polymers and organic electronic materials.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fragrance and flavor ingredients.

Basic Information

Product Name	4-(tert-Butyl)Picolinaldehyde
CAS No.	67141-22-4
Molecular Formula	C10H13NO
Molecular Weight	163.22 g/mol
Synonyms	4-(tert-Butyl)pyridine-2-carboxaldehyde; 2-Formyl-4-tert-butylpyridine; 4-tert-Butyl-2-pyridinecarboxaldehyde; 4-(1,1-Dimethylethyl)-2-pyridinecarboxaldehyde; 4-(tert-Butyl)picolinaldehyde; 4-tert-Butylpicolinaldehyde; 2-Pyridinecarboxaldehyde, 4-(1,1-dimethylethyl)-; 4-tert-Butyl-2-formylpyridine
EINECS	Contact for details

Quality Control

Our 4-(tert-Butyl)Picolinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.