Description

5-[(Acetyloxy)Methyl]-3A,6,7,7A-Tetrahydro-2-Methyl-(3Ar,5R,6S,7R,7Ar)-5H-Pyrano[3,2-D]Thiazole-6,7-Diol Diacetate (Ester) is a sophisticated chiral intermediate with significant synthetic utility. This compound is valued for its complex stereochemistry and functional groups, which make it a versatile building block in advanced organic synthesis. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly those targeting neurological or metabolic pathways.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to construct molecules with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the exploration of new chemical entities in drug discovery programs.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, agrochemicals, and high-value materials requiring specific stereochemical configurations.
• Academic Research: Used in university and institutional labs for methodological development in organic synthesis and stereochemistry.

Basic Information

Product Name	5-[(Acetyloxy)Methyl]-3A,6,7,7A-Tetrahydro-2-Methyl-(3Ar,5R,6S,7R,7Ar)-5H-Pyrano[3,2-D]Thiazole-6,7-Diol Diacetate (Ester)
CAS No.	67109-74-4
Molecular Formula	C16H21NO8S
Molecular Weight	387.40 g/mol
Synonyms	5-(Acetoxymethyl)-3a,6,7,7a-tetrahydro-2-methyl-(3aR,5R,6S,7R,7aR)-5H-pyrano[3,2-d]thiazole-6,7-diyl diacetate; (3aR,5R,6S,7R,7aR)-5-(Acetoxymethyl)-3a,6,7,7a-tetrahydro-2-methyl-5H-pyrano[3,2-d]thiazole-6,7-diyl diacetate; 5H-Pyrano[3,2-d]thiazole-6,7-diol diacetate derivative; Thiazole-fused pyran derivative; CAS 67109-74-4
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data, including HPLC chromatograms and spectroscopic evidence (NMR, IR, MS) to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles are available upon request. Our quality management system is designed to meet the stringent requirements of pharmaceutical R&D and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.