Description

Tetrakis(Trimethylsilyl)- Di-o-Methyloxime Of D-Arabino-Hexosulose is a specialized, high-purity organosilicon derivative of a sugar oxime, primarily used as a key synthetic intermediate and protecting group reagent in advanced organic synthesis. This compound is critical for researchers and process chemists requiring precise control over stereochemistry and functional group manipulation in complex molecule construction. It is particularly valuable in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of nucleoside analogs, carbohydrate-based drugs, and other bioactive molecules where the protection of hydroxyl groups is essential.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer therapies.
• Carbohydrate Chemistry: Used as a protecting group reagent for hydroxyl functions in the synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics.
• Fine Chemical Synthesis: Acts as a versatile intermediate in the production of specialty chemicals, chiral auxiliaries, and advanced materials requiring specific stereochemical configurations.
• Agrochemical Research: Employed in the development of new active ingredients, particularly those with sugar-based structures, for crop protection products.
• Process Chemistry & Scale-up: Provides a reliable and high-purity starting material for optimizing and scaling synthetic routes from laboratory to pilot plant scale.
• Academic & R&D: A valuable tool for methodological development in organic synthesis and for exploring new chemical spaces in medicinal chemistry programs.

Basic Information

Product Name	Tetrakis(Trimethylsilyl)- Di-o-Methyloxime Of D-Arabino-Hexosulose
CAS No.	67104-26-1
Molecular Formula	C22H52N2O7Si4
Molecular Weight	569.0 g/mol
Synonyms	D-Arabino-Hexosulose, Di-O-methyloxime, Tetrakis(trimethylsilyl) Derivative; 1,2:3,4-Di-O-isopropylidene-D-galacto-hexodialdo-1,5-pyranose Di-O-methyloxime Tetrakis(trimethylsilyl) Ether; Tetrakis-O-(trimethylsilyl)-Di-O-methyloxime of D-arabino-Hexosulose; TMS-protected D-galacto-hexodialdose dimethyloxime; (3aS,4R,6R,6aR)-6-(((1E,2E)-2-(Methoxyimino)-1-((trimethylsilyl)oxy)vinyl)oxy)-2,2,4-trimethyl-4-((((1E,2E)-2-(methoxyimino)-1-((trimethylsilyl)oxy)vinyl)oxy)methyl)tetrahydro-3aH-cyclopenta[d][1,3]dioxole-5,5-diyl bis(oxy)bis(trimethylsilane)
EINECS	Contact for details

Quality Control

Our Tetrakis(Trimethylsilyl)- Di-o-Methyloxime Of D-Arabino-Hexosulose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.