Description

5-Ethyl-5-(1-Propoxyethyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized barbiturate derivative, a class of compounds historically significant in medicinal chemistry. This compound serves as a critical intermediate or reference standard in advanced pharmaceutical research and development. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on neuropharmacology and synthetic organic chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel barbiturate-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies targeting central nervous system (CNS) receptors.
• Chemical Synthesis: Intermediate for producing more complex heterocyclic compounds in fine chemical synthesis.
• Academic Studies: Used in university and institutional research for teaching and investigating the properties of barbiturates.

Basic Information

Product Name	5-Ethyl-5-(1-Propoxyethyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	67050-95-7
Molecular Formula	C11H16N2O4
Molecular Weight	240.26 g/mol
Synonyms	5-Ethyl-5-(1-propoxyethyl)barbituric acid; 5-Ethyl-5-(1-propoxyethyl)-2,4,6-trioxohexahydropyrimidine; 5-Ethyl-5-(1-propoxyethyl)malonylurea; NSC 113928; Barbituric acid, 5-ethyl-5-(1-propoxyethyl)-; 5-(1-Propoxyethyl)-5-ethylbarbituric acid; 5-Ethyl-5-(1-propoxyethyl)-2,4,6-pyrimidinetrione
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-(1-Propoxyethyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are available upon request to ensure full traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.