Description

5-Ethyl-5-(1-Methyl-1-Nitroethyl)Barbituric Acid is a specialized barbiturate derivative with a unique nitroalkyl substitution. This compound is of significant interest in advanced pharmaceutical research and chemical synthesis due to its distinct molecular architecture. It serves as a critical intermediate for medicinal chemists and R&D laboratories developing novel therapeutic agents and studying structure-activity relationships.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of novel barbiturate-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in the synthesis of target molecules for studying central nervous system (CNS) activity and receptor binding.
• Chemical Synthesis Reference Standard: Serves as a high-purity standard for analytical method development and quality control in fine chemical production.
• Academic & Industrial R&D: Employed in universities and corporate R&D centers for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	5-Ethyl-5-(1-Methyl-1-Nitroethyl)Barbituric Acid
CAS No.	66968-90-9
Molecular Formula	C9H13N3O5
Molecular Weight	243.22 g/mol
Synonyms	5-Ethyl-5-(1-methyl-1-nitroethyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Ethyl-5-(1-methyl-1-nitroethyl)barbituric acid; 5-Ethyl-5-(1-methyl-1-nitroethyl)-1,3-diazinane-2,4,6-trione; 5-Ethyl-5-(1-methyl-1-nitroethyl)-2,4,6-trioxohexahydropyrimidine; 1-Methyl-1-nitropropyl barbituric acid derivative; Nitroalkyl barbiturate; Barbituric acid, 5-ethyl-5-(1-methyl-1-nitroethyl)-
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-(1-Methyl-1-Nitroethyl)Barbituric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.