Description

5-Ethyl-5-Isopropenylbarbituric Acid is a specialized barbiturate derivative with a unique isopropenyl side chain, offering distinct reactivity and structural properties. This compound serves as a crucial high-purity intermediate in advanced organic synthesis, particularly for the development of novel pharmaceutical actives and fine chemicals. It is primarily required by research institutions and pharmaceutical R&D departments focused on medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel barbiturate analogs and central nervous system (CNS) active compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new therapeutic agents.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes in pilot plants.
• Fine Chemical Synthesis: Intermediate for creating complex molecules with specific stereochemical or functional group requirements.
• Reference Standard: High-purity material for analytical method development and quality control in regulatory submissions.
• Academic Research: Used in university laboratories for studying heterocyclic chemistry and reaction mechanisms.

Basic Information

Product Name	5-Ethyl-5-Isopropenylbarbituric Acid
CAS No.	66968-60-3
Molecular Formula	C9H12N2O3
Molecular Weight	196.20 g/mol
Synonyms	5-Ethyl-5-(1-methylethenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Ethyl-5-isopropenylbarbituric acid; 5-Ethyl-5-(prop-1-en-2-yl)pyrimidine-2,4,6(1H,3H,5H)-trione; 5-Ethyl-5-(2-propen-2-yl)barbituric acid; Isopropenyl ethyl barbituric acid
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-Isopropenylbarbituric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We support cGMP compliance for pharmaceutical applications, and material can be supplied to meet specific customer or pharmacopeial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.