Description

5-Ethyl-5-Isobutyl-1-Methylbarbituric Acid is a specialized barbiturate derivative of significant interest in advanced chemical synthesis. This compound serves as a crucial high-purity intermediate for the research and development of novel pharmaceutical agents and fine chemicals. It is primarily required by pharmaceutical R&D laboratories and contract manufacturing organizations (CMOs) working on central nervous system (CNS) active ingredients and other specialized organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel barbiturate-based active pharmaceutical ingredients (APIs) and potential drug candidates.
• Chemical Research: Used as a reference standard or starting material in academic and industrial research focused on heterocyclic chemistry and medicinal chemistry.
• Fine Chemical Synthesis: Employed in the production of complex, high-value specialty chemicals requiring specific barbiturate core structures.
• Analytical Standard: Serves as a high-purity standard for quality control and method development in analytical laboratories using techniques like HPLC and GC.

Basic Information

Product Name	5-Ethyl-5-Isobutyl-1-Methylbarbituric Acid
CAS No.	66968-49-8
Molecular Formula	C11H18N2O3
Molecular Weight	226.27 g/mol
Synonyms	5-Ethyl-5-isobutyl-1-methyl-2,4,6(1H,3H,5H)-pyrimidinetrione; 1-Methyl-5-ethyl-5-isobutylbarbituric Acid; 5-Ethyl-5-(2-methylpropyl)-1-methyl-1,3-diazinane-2,4,6-trione; 1-Methyl-5-ethyl-5-isobutylbarbituric Acid; Butalbital Impurity/Intermediate; Barbituric Acid, 5-ethyl-5-isobutyl-1-methyl-
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-Isobutyl-1-Methylbarbituric Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment aligns with the standards expected for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.