Description

5-(1-Ethoxyethyl)-5-Ethylbarbituric Acid is a specialized barbiturate derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial high-purity intermediate for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily required by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel barbiturate-based or central nervous system (CNS) active pharmaceutical ingredients.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Serves as a critical starting material or intermediate for optimizing scalable synthetic routes under GMP conditions.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Intermediate for creating specialized chemicals used in agrochemicals or advanced material science.

Basic Information

Product Name	5-(1-Ethoxyethyl)-5-Ethylbarbituric Acid
CAS No.	66941-21-7
Molecular Formula	C10H16N2O4
Molecular Weight	228.25 g/mol
Synonyms	5-Ethyl-5-(1-ethoxyethyl)barbituric acid; 5-(1-Ethoxyethyl)-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Ethyl-5-(α-ethoxyethyl)barbituric acid; NSC 113928; Barbituric acid, 5-ethyl-5-(1-ethoxyethyl)-; 5-Ethyl-5-(1-ethoxyethyl)-1,3-diazinane-2,4,6-trione
EINECS	Contact for details

Quality Control

Our 5-(1-Ethoxyethyl)-5-Ethylbarbituric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.