Description

5,5-Diethyl-1-Phenethylbarbituric Acid is a specialized barbiturate derivative of significant interest in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for research into central nervous system (CNS) active agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic compounds and reference standards.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel barbiturate-based active pharmaceutical ingredients (APIs) and potential therapeutic agents.
• Chemical Reference Standard: Used in analytical laboratories for method development, calibration, and quality control testing of related substances.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies targeting GABAA receptors and other neurological targets.
• Academic & Institutional Research: Employed in universities and research institutes for pharmacological studies and the development of new chemical entities.
• Fine Chemical Synthesis: Building block for creating more complex, functionalized organic molecules in multi-step synthetic routes.

Basic Information

Product Name	5,5-Diethyl-1-Phenethylbarbituric Acid
CAS No.	66940-96-3
Molecular Formula	C16H20N2O3
Molecular Weight	288.34 g/mol
Synonyms	1-Phenethyl-5,5-diethylbarbituric Acid; 5,5-Diethyl-1-phenethyl-2,4,6(1H,3H,5H)-pyrimidinetrione; Phenethylbarbital; NSC 163501; Barbituric acid, 5,5-diethyl-1-phenethyl-; 1-(2-Phenylethyl)-5,5-diethylbarbituric acid
EINECS	Contact for details

Quality Control

Our 5,5-Diethyl-1-Phenethylbarbituric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Single impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.