Description

5,5-Diethyl-1-(2,2-Dimethylpropyl)Barbituric Acid is a specialized barbiturate derivative, a class of compounds historically significant in medicinal chemistry for their central nervous system depressant properties. This high-purity synthetic intermediate is critical for research and development in pharmaceutical synthesis, particularly for exploring novel therapeutic agents or studying structure-activity relationships. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and neuropharmacology research.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research-scale synthesis of novel barbiturate analogs and related central nervous system (CNS) active compounds.
• Medicinal Chemistry Research: Used in academic and industrial R&D for studying pharmacological profiles, metabolic pathways, and receptor binding affinities of barbiturate derivatives.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling in related pharmaceutical products.
• Biochemical Research: Utilized in studies investigating the mechanism of action of GABAA receptor modulators and other neurochemical processes.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of more complex, functionally specialized organic molecules in custom synthesis projects.

Basic Information

Product Name	5,5-Diethyl-1-(2,2-Dimethylpropyl)Barbituric Acid
CAS No.	66940-82-7
Molecular Formula	C13H22N2O3
Molecular Weight	254.33 g/mol
Synonyms	1-Neopentyl-5,5-diethylbarbituric Acid; 5,5-Diethyl-1-neopentylbarbituric Acid; 1-(2,2-Dimethylpropyl)-5,5-diethyl-2,4,6(1H,3H,5H)-pyrimidinetrione; 5,5-Diethyl-1-(2,2-dimethylpropyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; Neopentylbarbital; NSC 163047
EINECS	Contact for details

Quality Control

Our 5,5-Diethyl-1-(2,2-Dimethylpropyl)Barbituric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via techniques such as HPLC, NMR, and IR spectroscopy, to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.