Description

2-Piperidinecarboxylic Acid, 4-Methyl-, Ethyl Ester CAS NO 66937-93-7 is a high-purity piperidine derivative ester, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in providing a structurally defined scaffold for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and cardiovascular research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its piperidine core for biological activity.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in catalytic processes to induce enantioselectivity.
• Fine Chemical Production: Serves as a versatile building block for creating specialty chemicals, flavors, and fragrances.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological studies and exploring new chemical spaces.
• Peptidomimetics: The piperidine carboxylic acid ester structure is valuable for designing peptide analogs and conformationally restricted biomolecules.

Basic Information

Product Name	2-Piperidinecarboxylic Acid, 4-Methyl-, Ethyl Ester
CAS No.	66937-93-7
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	Ethyl 4-Methylpipecolate; Ethyl 4-Methyl-2-piperidinecarboxylate; 4-Methylpipecolic Acid Ethyl Ester; 4-Methyl-DL-pipecolic Acid Ethyl Ester; 2-Carbethoxy-4-methylpiperidine; 4-Methyl-2-piperidinecarboxylic Acid Ethyl Ester; NSC 334365; Ethyl 4-methylpipecolinate
EINECS	Contact for details

Quality Control

Our 2-Piperidinecarboxylic Acid, 4-Methyl-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets precise customer specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP and ISO compliant workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.