Description

Glycine, n-2-Propyn-1-Yl-, 1,1-Dimethylethyl Ester is a specialized amino acid derivative featuring a propargyl and a tert-butyl ester protecting group. This compound is a crucial protected glycine building block in organic synthesis, enabling the controlled introduction of the glycine moiety into complex molecular frameworks. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of peptides, peptidomimetics, and other bioactive molecules requiring protected glycine units.
• Agrochemical Research: Used in constructing novel amino acid-based fungicides, herbicides, and plant growth regulators.
• Chemical Biology & Proteomics: Serves as a building block for synthesizing probes and inhibitors that target specific enzymes or biological pathways.
• Peptide Synthesis (SPPS & Solution Phase): Provides a tert-butyl ester-protected, propargyl-modified glycine residue for custom peptide assembly.
• Material Science: Potential monomer or cross-linker in the development of functional polymers and smart materials via click chemistry.
• Academic & Industrial R&D: Essential reagent for methodological development in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Glycine, n-2-Propyn-1-Yl-, 1,1-Dimethylethyl Ester
CAS No.	66937-72-2
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	N-Propargylglycine tert-Butyl Ester; tert-Butyl N-(2-Propyn-1-yl)glycinate; Glycine, N-2-propyn-1-yl-, 1,1-dimethylethyl ester; N-(Prop-2-yn-1-yl)glycine tert-butyl ester; Boc-Gly(Propargyl)-OtBu (common abbreviation); 1,1-Dimethylethyl N-(2-propyn-1-yl)glycinate
EINECS	Contact for details

Quality Control

Our production of Glycine, n-2-Propyn-1-Yl-, 1,1-Dimethylethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and production applications. All materials are characterized by modern analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.