Description

Glycine, n-(2-Hydroxyethyl)-, 1,1-Dimethylethyl Ester is a protected amino acid derivative, specifically a tert-butyl ester of N-(2-hydroxyethyl)glycine, which serves as a crucial building block in organic synthesis. This compound matters because it provides a versatile handle for peptide coupling and chemical modification while offering orthogonal protection strategies for sensitive functional groups. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly peptides and peptidomimetics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific amino acid motifs.
• Peptide Chemistry: Serves as a protected glycine derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Bioconjugation: Facilitates the attachment of bioactive molecules to polymers, surfaces, or other biomolecules via its reactive ester and hydroxyl groups.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating custom molecular libraries.
• Specialty Surfactants & Polymers: Acts as a monomer or functional modifier in the synthesis of specialized polymers with tailored properties.

Basic Information

Product Name	Glycine, n-(2-Hydroxyethyl)-, 1,1-Dimethylethyl Ester
CAS No.	66937-71-1
Molecular Formula	C8H17NO3
Molecular Weight	175.23 g/mol
Synonyms	N-(2-Hydroxyethyl)glycine tert-butyl ester; 2-[(tert-Butoxycarbonyl)(2-hydroxyethyl)amino]acetic acid; tert-Butyl N-(2-hydroxyethyl)glycinate; Boc-N-(2-hydroxyethyl)glycine-OH; Glycine, N-(2-hydroxyethyl)-, 1,1-dimethylethyl ester; N-(2-Hydroxyethyl)glycine, tert-butyl ester; (tert-Butoxycarbonyl)(2-hydroxyethyl)aminoacetic acid
EINECS	Contact for details

Quality Control

Our Glycine, n-(2-Hydroxyethyl)-, 1,1-Dimethylethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.