Description

6-Chloro-5-Methylpyridine-3-Carboxylic Acid is a high-purity, versatile pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both a halogen substituent and a carboxylic acid group, which enables precise chemical modifications for creating complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the development of advanced herbicides, insecticides, and fungicides, leveraging its pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic and R&D Laboratories: Used in medicinal chemistry programs and methodological research to explore new chemical reactions and pathways.

Basic Information

Product Name	6-Chloro-5-Methylpyridine-3-Carboxylic Acid
CAS No.	66909-29-3
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	5-Methyl-6-chloronicotinic acid; 6-Chloro-5-methylnicotinic acid; 3-Carboxy-6-chloro-5-methylpyridine; 6-Chloro-5-methyl-3-pyridinecarboxylic acid; 6-Chloro-5-picolinic acid; 66909-29-3; 6-Chloro-5-methyl-pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 6-Chloro-5-Methylpyridine-3-Carboxylic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with relevant industry standards for fine chemical intermediates. A detailed Certificate of Analysis (COA), providing batch-specific data for identity, purity, and impurity profiles, is available for all shipments to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.