Description

3-[4-[Bis(2-Chloroethyl)Amino]-3-Methoxyphenyl]-2-Aminopropionic Acid is a specialized nitrogen mustard derivative with a phenylalanine backbone, designed for targeted chemical synthesis and research. This compound is valued for its role as a key intermediate in the development of novel pharmaceutical agents, particularly in oncology research. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of experimental therapeutics and biochemical probes.

Application

• Pharmaceutical Intermediate: A critical building block in the research and synthesis of potential anticancer agents and targeted therapies.
• Biochemical Research: Used in the study of alkylating agents and their mechanisms of action on biological macromolecules.
• Medicinal Chemistry: Serves as a precursor for the development of novel drug candidates with modified pharmacological profiles.
• Reference Standard: Employed as an analytical standard in quality control and method development for related pharmaceutical compounds.
• Academic Research: Utilized in university and institutional labs for chemical biology studies and structure-activity relationship (SAR) investigations.

Basic Information

Product Name	3-[4-[Bis(2-Chloroethyl)Amino]-3-Methoxyphenyl]-2-Aminopropionic Acid
CAS No.	66902-62-3
Molecular Formula	C₁₄H₂₀Cl₂N₂O₃
Molecular Weight	335.23 g/mol
Synonyms	DL-3-[p-[Bis(2-chloroethyl)amino]-m-methoxyphenyl]alanine; NSC 172112; 2-Amino-3-[4-[bis(2-chloroethyl)amino]-3-methoxyphenyl]propanoic acid; m-Methoxy-melphalan derivative; Phenylalanine nitrogen mustard analog; L-3-(4-[Bis(2-chloroethyl)amino]-3-methoxyphenyl)alanine; Alanine derivative with nitrogen mustard group
EINECS	Contact for details

Quality Control

Our 3-[4-[Bis(2-Chloroethyl)Amino]-3-Methoxyphenyl]-2-Aminopropionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.