Description

Exo-3,3-Dimethylbicyclo[2.2.1]heptane-2-propionic acid is a high-purity, synthetically derived carboxylic acid featuring a rigid, sterically defined bicyclic framework. This compound is valued as a versatile chiral building block and intermediate in advanced organic synthesis, where its unique three-dimensional structure imparts specific stereochemical and steric properties to target molecules. It is primarily needed by pharmaceutical R&D, agrochemical manufacturers, and specialty chemical producers for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its bicyclic structure can contribute to biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Material Science Research: Employed in the creation of novel polymers and specialty monomers with tailored physical properties due to its rigid, bulky architecture.
• Fragrance and Flavor Chemistry: Potential intermediate for synthesizing aroma chemicals with unique olfactory profiles derived from its camphor-like skeleton.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic synthesis and stereochemistry.

Basic Information

Product Name	Exo-3,3-Dimethylbicyclo[2.2.1]heptane-2-propionic Acid
CAS No.	66879-58-1
Molecular Formula	C₁₂H₂₀O₂
Molecular Weight	196.29 g/mol
Synonyms	2-Exo-(3,3-Dimethyl-2-norbornyl)propionic Acid; 2-(3,3-Dimethylbicyclo[2.2.1]hept-2-yl)propanoic Acid (exo-); 3,3-Dimethyl-2-norbornanepropionic Acid (exo-); exo-3,3-Dimethyl-2-norbornanepropanoic Acid; exo-2-(3,3-Dimethylnorbornan-2-yl)propionic Acid; (1R,2S,4S)-rel-3,3-Dimethylbicyclo[2.2.1]heptane-2-propanoic Acid; Bicyclo[2.2.1]heptane-2-propanoic acid, 3,3-dimethyl-, exo-
EINECS	Contact for details

Quality Control

Our Exo-3,3-Dimethylbicyclo[2.2.1]heptane-2-propionic acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets exacting R&D and production standards. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (exo- isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.